In What Ways Do Synthetic Nucleotides and Natural Base Lesions Alter the Structural Stability of G-Quadruplex Nucleic Acids?

Figure 8

Structures of syn 8-furyl-dG (1); 8-(4-cyanophenyl)guanine (2); anti 8-vinyl-benzothienyl-dG (3); 8-acetylphenylguanine (4); 8-vinyl-acetylphenylguanine (5); 8-benzothienylguanine (6); 8-(pyren-1-yl)guanine (7); 2-aminopurine (8); 5-nitroindole (9); and 5-furyl-2′-deoxyuridine (10).