Thermodynamic and Structural Analysis of DNA Damage Architectures Related to Replication
Figure 3
Structural differences in the design of some previously used substrates (left) and herein (right) in characterizing the thermodynamic contribution of a single-stranded DNA region or terminal phosphate () on the stability of the core dsDNA. Oligonucleotides designed for dangling ends and terminal phosphates are self-complementary, while the evaluation of a single overhang or phosphate does not require self-complementary sequences.
