Direct Detection of Thrombin Binding to 8-Bromodeoxyguanosine-Modified Aptamer: Effects of Modification on Affinity and Kinetics

<table>Structure of (a) G-quadruplex of thrombin binding aptamer and (b) 8-bromodeoxyguanosine. Modification sites, G1 and G10, are indicated in red.</table>

Journal of Nucleic Acids

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Figure 1

Figure 1: Direct Detection of Thrombin Binding to 8-Bromodeoxyguanosine-Modified Aptamer: Effects of Modification on Affinity and Kinetics 