Modulation of Arginase-2 mRNA Levels by <i>ω</i>-3 PUFAs and Aspirin in Asthmatic Human Lung Fibroblasts

<div>The effects of RvD1 and T<sub>H</sub>1 cytokines on mRNA levels of genes involved in arginine metabolism in DHLF. ARG2 (a), ODC (b), and OAT (c) mRNA levels were determined in DHLF. DHLF were treated with 1 <i>μ</i>M RvD1, T<sub>H</sub>1 cytokine cocktail (25 ng/mL TNF-<i>α</i>, 10 ng/mL IFN-<i>γ</i>, and 100 ng/mL IL- 1<i>β</i>), or both for 24 hours. RNA was then extracted from DHLF and analyzed by RT-qPCR. Data were statistically analyzed using randomized block ANOVA, followed by Tukey’s multiple comparisons test. 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Journal of Lipids

fig2

Figure 2

Figure 2: Modulation of Arginase-2 mRNA Levels by <i>ω</i>-3 PUFAs and Aspirin in Asthmatic Human Lung Fibroblasts 

Journal of Lipids

Modulation of Arginase-2 mRNA Levels by ω-3 PUFAs and Aspirin in Asthmatic Human Lung Fibroblasts

Figure 2