Developing a Modified Low-Density Lipoprotein (M-LDL-C) Friedewald’s Equation as a Substitute for Direct LDL-C Measure in a Ghanaian Population: A Comparative Study

Table 1

Distribution of basic lipoprotein measurements.

	TC	TG	HDL	Non-HDL	D-LDL-C	F-LDL-C	N-LDL-C	A-LDL-C	M-LDL-C
	mmol/L	mmol/L	mmol/L	mmol/L	mmol/L	mmol/L	mmol/L	mmol/L	mmol/L
Mean	4.60	1.02	1.38	3.22	2.47	2.76	2.74	2.99	2.97
SD	1.20	0.57	0.36	1.13	0.71	1.05	1.04	1.02	1.08
1st Quartile	3.77	0.65	1.13	2.45	1.94	2.03	2.03	2.30	2.23
Median	4.45	0.88	1.33	3.09	2.43	2.64	2.63	2.87	2.64
3rd Quartile	5.21	1.23	1.59	3.78	2.90	3.28	3.26	3.54	3.28

p<0.001: significant in comparison to D-LDL-C. TC: total cholesterol; TG: triglycerides; HDL-C: high-density lipoprotein cholesterol; LDL-C: low-density lipoprotein cholesterol; D-LDL-C: directly measured LDL-C; FLDL-C LDL-C calculated by Friedewald’s formula; N-LDL-C, LDL-C calculated by Martin’s formula; A-LDL-C, LDL-C calculated by Anandaraja’s formula; M-LDL-C, LDL-C calculated by modified formula.