5-Lipoxygenase-Activating Protein as a Modulator of Olanzapine-Induced Lipid Accumulation in Adipocyte
Figure 5
Effect of 10 μM MK-886 in the presence of increasing concentrations of olanzapine on intracellular lipid content. 3T3-L1 cells were differentiated into adipocytes in the presence and absence of indicated drugs. Samples were collected 5 days after the initiation of the differentiation protocol. Results (mean ± SEM; ) are expressed as optical density (O.D.) readings at 520 nm. *, ** versus the corresponding group without olanzapine; # versus the corresponding group without MK-886.