The NLRP3 Genetic Variant (rs10754555) Reduces the Risk of Adverse Outcome in Middle-Aged Patients with Chronic Coronary Syndrome

Table 5

Relatively quantified gene expression (mRNA levels) of NLRP3, TLR4, IL-1β, and IL-18 genes as related to NLRP3 genotypes in the total population.

	CC	CG	GG	^1 value	^2 value
NLRP3	0.666 (0.522, 0.894)	0.674 (0.470, 0.917)	0.709 (0.529, 0.950)	0.820	0.865
TLR4	0.815 (0.605, 1.093)	0.846 (0.610, 1.182)	0.746 (0.581, 1.055)	0.419	0.709
IL-1β	1.095, (0.829, 1.545)	1.168 (0.819, 1.614)	1.123 (0.855, 1.499)	0.777	0.668
IL-18	0.680 (0.530, 0.876)	0.660 (0.525, 0.870)	0.664 (0.520, 0.849)	0.884	0.620

¹ values represent the difference between genotypes (Kruskal-Wallis test). ² values represent the difference between homozygous wild type (CC) and the G-allele (CG and GG combined) (Mann–Whitney test).