The NLRP3 Genetic Variant (rs10754555) Reduces the Risk of Adverse Outcome in Middle-Aged Patients with Chronic Coronary Syndrome
Table 4
Baseline characteristics of the total population according to age dichotomized at 56 years.
Baseline characteristics
≤56 years ()
>56 years ()
value
Men/women ( (%))
210/38 (85/15)
572/180 (76/24)
0.004
Type 2 diabetes mellitus ( (%))
46 (19)
154 (20)
0.51
Previous MI ( (%))
112 (45)
325 (43)
0.59
Previous stroke ( (%))
0 (0)
27 (3.6)
0.002
Hypertension ( (%))
110 (44)
445 (59)
<0.001
Current smokers ( (%))
80 (32)
123 (16)
<0.001
BMI (kg/m2)
27.4 (24.8, 30.1)
27.0 (24.8, 29.4)
0.23
Metabolic syndrome
62 (25)
182 (24)
0.81
Total cholesterol (mmol/L)
4.6 (1.1)
4.5 (0.9)
0.25
HDL cholesterol (mmol/L)
1.2 (0.4)
1.4 (0.4)
<0.001
LDL cholesterol (mmol/L)
2.6 (0.9)
2.5 (0.8)
0.27
Triglycerides (mmol/L)
1.47 (1.03, 2.24)
1.26 (0.91, 1.76)
<0.001
Fasting glucose (mmol/L)
6.1 (2.3)
6.0 (1.8)
0.75
Medication (%)
Statins
243 (98)
739 (98)
0.91
β-Blockers
177 (71)
580 (77)
0.20
Nitrates
46 (19)
171 (23)
0.17
ACE inhibitors
61 (25)
202 (27)
0.50
ARB
8 (3)
36 (5)
0.09
CCB
60 (24)
195 (26)
0.62
Diuretics
35 (14)
190 (25)
<0.001
Insulin
10 (4)
34 (6)
0.75
Oral antidiabetics
26 (10)
92 (12)
0.46
No antidiabetics
14 (6)
46 (6)
0.79
MI: myocardial infarction; SD: standard deviation; BMI: body mass index; HDL: high-density lipoprotein; LDL: low-density lipoprotein; ACE: angiotensin converting enzyme; ARB: angiotensin receptor blocker; CCB: calcium channel blocker. values are chi-square test for categorical variables and -test and Mann–Whitney test for continuous variables, referring to differences between patients with and without endpoints. Median levels (25 and 75 percentiles). Bolded texts indicate statistically significant values.
