The NLRP3 Genetic Variant (rs10754555) Reduces the Risk of Adverse Outcome in Middle-Aged Patients with Chronic Coronary Syndrome

Table 3

Frequency of the NLRP3 variant according to comorbidity at baseline.

		CC	CG	GG	G-allele freq.	value
Previous MI	+	192	186	57	0.345	0.147
	-	222	262	77	0.375
Previous stroke	+	11	13	2	0.327	0.942
	-	403	434	132	0.360
Diabetes	+	78	89	32	0.385	0.448
	-	336	359	102	0.353
Mets	+	101	110	33	0.360	0.938
	-	313	337	101	0.359
Hypertension	+	228	246	82	0.368	0.687
	-	186	202	52	0.348
Current smoker	+	75	102	24	0.373	0.177
	-	338	346	110	0.359
		222	214	61	0.339	0.050
		192	233	73	0.381

MI: myocardial infarction; Mets: metabolic syndrome; BMI: body mass index dichotomized at the median level. values represent the difference in G-allele frequency (CG and GG combined) according to presence of comorbidity (chi-square test).