The NLRP3 Genetic Variant (rs10754555) Reduces the Risk of Adverse Outcome in Middle-Aged Patients with Chronic Coronary Syndrome

Figure 3

Levels of circulating IL-6, hs CRP, IL-18, and IL-12 according to NLRP3 genotypes Blue, orange, and pale orange columns represent homozygous wild type (CC), heterozygous (CG), and homozygous of the gene variant (GG), respectively. Results are dichotomized according to age at the 25 percentile level (56 years). values represent difference in circulating levels of each marker between the CC genotype and CG/GG combined (Mann–Whitney test).