DNA Vaccine Treatment in Dogs Experimentally Infected with Trypanosoma cruzi
Table 2
Abnormal electrocardiographic features in dogs experimentally infected with T. cruzi and treated with the DNA vaccine at 3, 6, and 12 months postinfection (mpi).
Group
Suggested pathological conditions by EKG recordings [78, 79]
Affected dogs (dogs/) at 3 mpi
Affected dogs (dogs/) at 6 mpi
Affected dogs (dogs/) at 12 mpi
Inf/SS mock-treated
AV block+infarction
20% (1/5)
Ischemia
20% (1/5)
MEAD to the left+LBBB+infarction+ventricle enlargement
20% (1/5)
MEAD to the right+RBBB+infarction+ventricle enlargement
60% (3/5)
Arrhythmia+MEAD to the left+ventricle enlargement
20% (1/5)
Ischemia+MEAD to the right+ventricle enlargement
60% (3/5)
pBCSSP4
AV block
20% (1/5)
LBBB
20% (1/5)
MEAD to the right+RBBB+infarction
20% (1/5)
MEAD to the left+LBBB+AV block
20% (1/5)
LBBB+infarction+ischemia
40% (2/5)
20% (1/5)
RBBB+ischemia
40% (2/5)
pBCSP
AV block
20% (1/5)
Infarction
20% (1/5)
Infarction+ischemia
20% (1/5)
20% (1/5)
Arrhythmia+AV block
20% (1/5)
Mixture
AV block+infarction+RBBB
20% (1/5)
Ischemia
20% (1/5)
20% (1/5)
Arrhythmia+ischemia
20% (1/5)
AV block+ischemia
20% (1/5)
20% (1/5)
pBK-CMV
Arrhythmia+ischemia
20% (1/5)
MEAD to the left+ventricle enlargement
40% (2/5)
MEAD to the left+LBBB+infarction+ventricle enlargement
20% (1/5)
Arrhythmia+MEAD to the right+ventricle enlargement+ischemia
20% (1/5)
MEAD to the right+RBBB+ventricle enlargement+infarction+ischemia
40% (2/5)
Ventricle enlargement
20% (1/5)
Arrhythmia+MEAD to the left+ventricle enlargement
20% (1/5)
Arrhythmia+ventricle enlargement+ischemia+MIMI
20% (1/5)
Group descriptions are shown in Table 1. mpi = months postinfection; Inf = infected; AV = atrioventricular; LBBB = left bundle branch block; RBBB = right bundle branch block; MEAD = mean electrical axis deviation; MIMI = microscopic intramural myocardial infarction.