Whole Blood Stimulation Assay as a Treatment Outcome Monitoring Tool for VL Patients in Ethiopia: A Pilot Evaluation

Figure 2

IFN-γ (a), TNF-α (b), IP-10 (c), IL-2 (d), and IL-10 (e) levels in soluble L. infantum antigen-stimulated plasma of 13 VL patients at the active moment (D0), during one week of treatment (W1), and the end of treatment (EOT). Each line curve represents an individual during follow-up. Comparison of medians was made using the Wilcoxon paired -test. ; ; . Dotted lines represent the best cut-off for each cytokine/chemokine based on ROC analyses to discriminate the active from cured status.

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