Whole Blood Stimulation Assay as a Treatment Outcome Monitoring Tool for VL Patients in Ethiopia: A Pilot Evaluation

Figure 1

IFN-γ (a), TNF-α (b), IP-10 (c), IL-2 (d), and IL-10 (e) levels in soluble L. donovani antigen-stimulated plasma of 13 VL patients at active disease (D0), after one week of treatment (W1), and at the end of treatment (EOT). Each line curve represents an individual during follow-up. Comparison of medians was made using the Wilcoxon paired -test. ; ; . Dotted line represents the best cut-off for each cytokine/chemokine based on ROC analyses to discriminate active from cured status.

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