The Potential Role of Regulatory B Cells in Idiopathic Membranous Nephropathy

Figure 1

The source of Breg. Different from Treg, Breg has more extensive sources. It does not matter whether they are B1 cells or B2 cells, or if they are immature B cells or mature B cells, under certain conditions of stimulation, Breg with immunomodulation function can be differentiated. At present, the main mechanism by which Breg plays the immune regulatory function in the human body is the secretion of IL-10.