Enriched LPS Staining within the Germinal Center of a Lymph Node from an HIV-Infected Long-Term Nonprogressor but Not from Progressors

Figure 1

Identification of LPS staining in lymph nodes of two HIV-negative donors, three ART-naïve chronically HIV-infected progressors, and one chronically HIV-infected LTNP. Representative images of unselected lymph node (LN) sections stained for LPS-core antigen (red, 200x and 400x). The LTNP showed increased LPS infiltration within the germinal center; the progressors showed increased LPS infiltration in the LNs with impaired structures of the germinal center; LPS staining was rarely detected from the HIV-negative donors.