Research Article
Epitope-Based Peptide Vaccine against Glycoprotein G of Nipah Henipavirus Using Immunoinformatics Approaches
Table 2
Most potential T cell epitopes interacting with MHC class I alleles, their positions, IC50, rank, and conservancy.
| Peptide | Start | End | Allele | IC50 | Rank | Conservancy |
| FAYSHLERI | 229 | 237 | HLA-A02:01 | 376.44 | 2.5 | | 229 | 237 | HLA-A02:03 | 19.03 | 0.37 | | 229 | 237 | HLA-A02:06 | 23.3 | 0.28 | 76.19 | 229 | 237 | HLA-A68:02 | 104.31 | 0.63 | | 229 | 237 | HLA-B51:01 | 133.03 | 0.02 | | 229 | 237 | HLA-B53:01 | 222.39 | 0.21 | | 229 | 237 | HLA-C03:03 | 57.38 | 0.22 | | 229 | 237 | HLA-C06:02 | 112.27 | 0.05 | | 229 | 237 | HLA-C07:01 | 151.15 | 0.05 | | 229 | 237 | HLA-C12:03 | 13.37 | 0.03 | | 229 | 237 | HLA-C15:02 | 207.16 | 0.12 | |
| FLIDRINWI | 512 | 520 | HLA-A02:01 | 3.65 | 0.02 | | 512 | 520 | HLA-A02:03 | 2.32 | 0.02 | | 512 | 520 | HLA-A02:06 | 4.71 | 0.04 | 100 | 512 | 520 | HLA-A68:02 | 488.4 | 1.8 | | 512 | 520 | HLA-C03:03 | 366.48 | 0.63 | | 512 | 520 | HLA-C06:02 | 163.19 | 0.07 | | 512 | 520 | HLA-C07:01 | 416.5 | 0.12 | | 512 | 520 | HLA-C12:03 | 55.27 | 0.13 | |
| FSWDTMIKF | 458 | 466 | HLA-A02:06 | 131.35 | 1.3 | | 458 | 466 | HLA-A29:02 | 328.77 | 1.2 | | 458 | 466 | HLA-B35:01 | 70.16 | 0.24 | 100 | 458 | 466 | HLA-B46:01 | 470.72 | 0.09 | | 458 | 466 | HLA-B53:01 | 95.8 | 0.12 | | 458 | 466 | HLA-B57:01 | 380.38 | 0.93 | | 458 | 466 | HLA-B58:01 | 313.77 | 0.77 | | 458 | 466 | HLA-C12:03 | 35.09 | 0.09 | |
| KLISYTLPV | 201 | 209 | HLA-A02:01 | 2.36 | 0.02 | | 201 | 209 | HLA-A02:03 | 2.4 | 0.02 | | 201 | 209 | HLA-A02:06 | 3.77 | 0.02 | 100 | 201 | 209 | HLA-A30:01 | 146.34 | 0.44 | | 201 | 209 | HLA-A32:01 | 21.39 | 0.04 | | 201 | 209 | HLA-B15:01 | 303.74 | 1.3 | | 201 | 209 | HLA-C14:02 | 187.05 | 0.28 | | 201 | 209 | HLA-C15:02 | 364.98 | 0.2 | |
| TVYHCSAVY | 278 | 286 | HLA-A03:01 | 84.04 | 0.35 | | 278 | 286 | HLA-A11:01 | 263.53 | 1.6 | | 278 | 286 | HLA-A26:01 | 363.08 | 0.19 | | 278 | 286 | HLA-A29:02 | 10.13 | 0.08 | 100 | 278 | 286 | HLA-A30:02 | 32.49 | 0.07 | | 278 | 286 | HLA-A68:01 | 310.51 | 1.7 | | 278 | 286 | HLA-B15:01 | 71.72 | 0.41 | | 278 | 286 | HLA-B15:02 | 353.64 | 0.13 | | 278 | 286 | HLA-B35:01 | 27.98 | 0.12 | | 278 | 286 | HLA-C12:03 | 45.95 | 0.11 | | 278 | 286 | HLA-C14:02 | 103.08 | 0.18 | |
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