Reverse Immunology Approach to Define a New HIV-gp41-Neutralizing Epitope

<table class="table-group" id="tab1"><tr><td><table class="table"><tr><td class="thead-hr" colspan="8"><hr/></td></tr><tr class="thead"><td class="align_left" rowspan="2">Virus</td><td class="align_center" colspan="7">TZM-bl assay</td></tr><tr class="thead"><td class="align_center">NL4.3</td><td class="align_center">JRCSF</td><td class="align_center">YU-2</td><td class="align_center">ADA</td><td class="align_center">TRO.11</td><td class="align_center">QHO692.44</td><td class="align_center">ZM249M.Pl1</td></tr><tr><td class="thead-hr" colspan="8"><hr/></td></tr><tr><td class="align_left">Tier</td><td class="align_center">1</td><td class="align_center">2</td><td class="align_center">2</td><td class="align_center">2</td><td class="align_center">2</td><td class="align_center">2</td><td class="align_center">2</td></tr><tr><td class="align_left">Clade</td><td class="align_center">B</td><td class="align_center">B</td><td class="align_center">B</td><td class="align_center">B</td><td class="align_center">B</td><td class="align_center">B</td><td class="align_center">C</td></tr><tr><td class="align_left">IC<sub>50</sub> (<i>μ</i>g/mL)</td><td class="align_center">0.4</td><td class="align_center">2.4</td><td class="align_center">9.7</td><td class="align_center">1.7</td><td class="align_center">2.3</td><td class="align_center">3.1</td><td class="align_center">4.7</td></tr><tr class="table-tr"><td colspan="8"><hr class="tbody-hr"/></td></tr></table></td></tr></table>

<div>Neutralizing activity of F8 mAb on tier 1 and tier 2 HIV-1 clade B and clade C strains.</div>

Journal of Immunology Research

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Table 1

Table 1: Reverse Immunology Approach to Define a New HIV-gp41-Neutralizing Epitope 