Review Article
Dysregulated Functions of Lung Macrophage Populations in COPD
Table 2
Molecules differentially expressed by monocytes or IMs from animals or patients with COPD compared to healthy controls.
| Molecule family | Encoded proteins | References |
| Cytokines | TNF-α ↓, IL-6 ↑ | [146, 245] | Chemokines | CCL2 ↑, IL-8 ↓ | [146, 252] | Chemokine receptors | CCR2 ↑ | [253] | Metalloproteinases | MMP-9 ↓, Mmp-12 ↑ | [146, 251] | Antigen presentation molecules | CD86 ↓ | [252] | Integrins, PRRs | CD11b ↓, CD14 ↓, CD54 ↓ | [146, 252] | MicroRNAs | miR-24-3p ↑, miR-93-5p ↑, miR-320a ↑, miR-320b ↑, miR1273g-3p ↓ | [254] |
|
|