Cardiac Function Remains Impaired Despite Reversible Cardiac Remodeling after Acute Experimental Viral Myocarditis
Table 1
Gravimetric characteristics and hemodynamic function of C57BL/6J mice 7 and 28 days after CVB3 infection.
Control
CVB3, 7 days p.i.
Change
CVB3, 28 days p.i.
Change
Body weight [g]
−24%
−17%
LV weight [mg]
−35%
−35%
Global function
Heart rate [bpm]
−9%
−19%
Cardiac output [mL/min]
−47%
−56%
Stroke volume [μL]
−42%
−46%
Stroke work [μL⋅mmHg]
−62%
−58%
Systolic function
[mmHg]
−43%
−17%
d/ [mmHg/s]
−58%
−50%
[μL]
+16%
−12%
Diastolic function
[mmHg]
+76%
+22%
dP/ [mmHg/s]
−65%
−43%
Tau [ms]
+65%
+59%
[μL]
−17%
−32%
Data are presented as mean ± SEM. different compared to noninfected mice (control); ; ; ; ; . No significances found between CVB3 (7 days) and CVB3 (28 days).
