The Role of NK Cells in Pig-to-Human Xenotransplantation

Figure 1

NK cytotoxicity against 2A2 pig endothelial cells. (a) Monolayers of porcine endothelial cells (pEC) were cultured to confluence and a suspension of IL2-activated purified polyclonal NK cells (bright round cells) was added on top of the monolayer, always in the absence of human sera. (b) After 4 hours of coculture with IL2-activated NK cells, the pEC monolayer was destroyed. Pictures were taken with a 200x magnification.

(a)

(b)