Roles of Zinc Signaling in the Immune System

Figure 7

Zn-signal axes in immune system. Each Zn-signal axis targets a specific molecule and controls a variety of cellular activities such as proliferation, differentiation, survival, migration, and function via a distinct signaling pathway to control immune homeostasis and functions. ZnD (red) impairs these Zn-signal axes and leads to disease if there is no redundant machinery.