Regulation of Neutrophil Degranulation and Cytokine Secretion: A Novel Model Approach Based on Linear Fitting

Figure 5

Linear fitting of LPS-mediated kinetics of cytokine release and degranulation in human neutrophils. Enlisted cytokines on the histograms fitted to the kinetics of the degranulation markers characteristic for (a) azurophil granules (CD63), (b) specific granules (CD66b), (c) gelatinase granules (CD11b), and (d) secretory vesicles (CD45), according to the selection of value ≤ 0.05 and RSQ ≥ 0.82.

(a)

(b)

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(d)