Research Article

Regulation of Neutrophil Degranulation and Cytokine Secretion: A Novel Model Approach Based on Linear Fitting

Figure 1

Time-dependent effect of LPS on cytokine secretion in human neutrophils. Cytokine secretion was measured by CBA upon stimulation with 100 ng/mL LPS for 0 h, 2 h, 4 h, 6 h, 12 h, and 24 h. Results are mean secretion (pg/mL) ± SEM of at least 3 independent experiments, significantly different from cytokine secretion in nonstimulated control at the corresponding time: , , , and .