Utilities for High-Throughput Analysis of B-Cell Clonal Lineages

Figure 3

Phylogenetic trees for case studies discussed in this paper. (a) VH4-34 lineage in the human tonsil (84 sequences); (b) heavy chain clonal family from a 2-week-old zebrafish (43 sequences); (c) developmental lineage of the HIV bnAb CAP256-VRC26 over 8 timepoints (692 sequences). Larger copies of these trees, plus other output from AnnotateTree, can be found in the Supplementary Information.

(a)

(b)

(c)