Inhibition of Neutrophil Collagenase/MMP-8 and Gelatinase B/MMP-9 and Protection against Endotoxin Shock

Table 2

Peptide treatment strategy for the animal experiments in Figure 1.

Group	Peptide administration strategy
G1 ( = 12 or 15)	LPS (100 μL^*, iv)
G2 ( = 12)	LPS (100 μL, iv), 5 minutes later, Regasepin 2 (100 μL^**, iv)
G3 ( = 12)	LPS (100 μL, iv), 5 minutes later, P2 (100 μL^***, iv)

LPS is dissolved in sterile 0.9% saline at a concentration of 2 μg/µL. Regasepin 2 was dissolved in sterile 0.9% saline at a concentration of 7 mg/mL. Peptide is dissolved in sterile 0.9% saline at a concentration of 17.7 mg/mL for the experiment in Figure 1(a), 5.9 mg/mL for Figure 1(b), and 1.97 mg/mL for Figure 1(c).