Inhibition of Neutrophil Collagenase/MMP-8 and Gelatinase B/MMP-9 and Protection against Endotoxin Shock

Figure 3

Plasma concentrations of P2 versus time after an intravenous bolus injection. (a) The profiles of P2 at a dose of 90 mg/kg in five individual mice were averaged. The data point at time 0 is not shown. (b) The profiles of P2 plasma concentrations versus time after intravenous injection of 90, 30, or 10 mg/kg P2 were shown. (c) For a clear observation of the profiles in (b), the data from time point 9 to 30 minutes were magnified.

(a)

(b)

(c)