Serum Levels of TNF-α, IL-12/23p40, and IL-17 in Plaque Psoriasis and Their Correlation with Disease Severity

Table 4

Results of multiple linear regression analysis for PASI.

Variables	Unstandardized coefficients		Standardized coefficients		value	95.0% confidence interval for
		Std. error	Beta			Lower bound	Upper bound
(Constant)	6.038	3.544		1.704	0.102	−1.294	13.370
Age	0.339	0.317	1.453	1.073	0.295	−0.315	0.994
Gender	0.523	1.303	0.066	0.402	0.692	−2.171	3.218
Psoriasis onset	−0.265	0.315	−1.281	−0.841	0.409	−0.917	0.387
Duration	−0.483	0.330	−0.917	−1.464	0.157	−1.165	0.199
Family history	−0.150	1.519	−0.016	−0.099	0.922	−3.291	2.992
TNF-	−0.520	0.335	−0.283	−1.552	0.134	−1.212	0.173
IL-12/IL-23p40	0.016	0.012	0.259	1.377	0.182	−0.008	0.041
IL-17	−0.145	0.169	−0.138	−0.859	0.399	−0.495	0.205
			Adjusted	Std. error of the estimate			value
Model summary	0.700	0.489	0.312	3.02314			0.027^*

Dependent variable: PASI; predictors: (constant), age, gender, age at psoriasis onset, duration, family history, TNF-, IL-12/IL-23p40, and IL-17; ^*statistically significant.