Serum Levels of TNF-α, IL-12/23p40, and IL-17 in Plaque Psoriasis and Their Correlation with Disease Severity

Table 2

Serum levels of TNF-α, IL-12/23p40, and IL-17 in psoriatic patients and controls.

Cytokines	Psoriatic patients; ( = 32)	Controls; ( = 32)	values
TNF-α (pg/mL)
Mean ± SD	7.45 ± 1.98	4.21 ± 1.80	0.000^*
Median (min–max)	7.41; (2.23–10.80)	3.84; (1.80–7.13)
IL-12/23p40 (pg/mL)
Mean ± SD	93.63 ± 58.20	91.51 ± 45.89	0.968
Median (min–max)	60.02; (36.18–198.34)	93.75; (26.10–207.51)
IL-17 (pg/mL)
Mean ± SD	2.67 ± 3.46	1.80 ± 2.81	0.311
Median (min–max)	0.45; (0.00–8.59)	0.00; (0.00–11.35)

Mann-Whitney test; ^*statistically significant.