Research Article
Serum Levels of TNF-α, IL-12/23p40, and IL-17 in Plaque Psoriasis and Their Correlation with Disease Severity
Table 1
Patients’ demographic and clinical characteristics, as well as cytokine serum levels.
| Psoriatic patients ( = 32) | Controls ( = 32) | Patient number | Age (years) | Gender | Age at onset (years) | Disease duration (years) | Family history | PASI (0–72) | TNF-α (pg/mL) | IL-12/23p40 (pg/mL) | IL-17 (pg/mL) | TNF-α (pg/mL) | IL-12/23p40 (pg/mL) | IL-17 (pg/mL) |
| 1 | 72.00 | Female | 71.00 | 1.00 | No | 15.00 | 7.69 | 198.34 | 0.00 | 5.41 | 72.08 | 0.00 | 2 | 45.00 | Female | 22.00 | 13.00 | No | 6.40 | 7.69 | 50.02 | 2.56 | 1.80 | 103.33 | 1.42 | 3 | 43.00 | Female | 21.00 | 22.00 | No | 2.20 | 7.71 | 185.86 | 6.28 | 5.57 | 35.75 | 1.42 | 4 | 57.00 | Male | 52.00 | 5.00 | No | 6.20 | 7.37 | 59.26 | 8.59 | 4.56 | 103.33 | 11.35 | 5 | 62.00 | Female | 47.00 | 15.00 | No | 5.40 | 7.40 | 142.79 | 4.75 | 3.53 | 44.86 | 0.00 | 6 | 42.00 | Female | 41.00 | 1.00 | No | 2.80 | 7.06 | 62.68 | 8.59 | 2.68 | 112.40 | 0.00 | 7 | 52.00 | Female | 50.00 | 2.00 | No | 2.20 | 7.69 | 116.88 | 0.00 | 1.96 | 51.69 | 0.00 | 8 | 40.00 | Male | 25.00 | 15.00 | No | 2.20 | 10.80 | 51.74 | 0.00 | 5.96 | 207.51 | 1.42 | 9 | 23.00 | Male | 13.00 | 10.00 | Yes | 2.30 | 5.66 | 45.18 | 0.00 | 7.13 | 93.25 | 0.00 | 10 | 23.00 | Female | 10.00 | 13.00 | No | 4.10 | 2.34 | 48.36 | 0.45 | 1.98 | 150.20 | 0.00 | 11 | 30.00 | Female | 10.00 | 20.00 | Yes | 6.30 | 4.77 | 59.71 | 0.45 | 3.84 | 65.02 | 0.00 | 12 | 71.00 | Female | 69.00 | 2.00 | No | 14.90 | 6.63 | 196.34 | 0.00 | 4.41 | 34.86 | 0.00 | 13 | 23.00 | Male | 22.00 | 1.00 | No | 9.40 | 7.37 | 60.33 | 1.96 | 2.80 | 110.38 | 0.00 | 14 | 37.00 | Male | 24.00 | 13.00 | No | 3.70 | 7.03 | 152.85 | 8.45 | 4.57 | 98.29 | 0.00 | 15 | 53.00 | Female | 49.00 | 4.00 | Yes | 5.20 | 10.60 | 56.27 | 8.58 | 4.66 | 166.01 | 0.00 | 16 | 62.00 | Female | 60.00 | 2.00 | No | 7.40 | 10.40 | 114.79 | 3.18 | 5.83 | 94.25 | 5.67 | 17 | 29.00 | Female | 16.00 | 13.00 | No | 5.30 | 7.74 | 38.68 | 7.80 | 3.28 | 136.36 | 9.49 | 18 | 69.00 | Male | 44.00 | 25.00 | No | 3.20 | 7.37 | 177.88 | 1.00 | 2.19 | 97.28 | 1.80 | 19 | 34.00 | Female | 25.00 | 9.00 | Yes | 3.10 | 2.23 | 60.74 | 0.00 | 7.10 | 73.09 | 4.26 | 20 | 25.00 | Male | 21.00 | 4.00 | No | 5.10 | 7.71 | 56.18 | 0.00 | 7.13 | 39.70 | 2.60 | 21 | 67.00 | Female | 56.00 | 11.00 | No | 5.20 | 8.37 | 51.36 | 0.00 | 2.10 | 26.65 | 0.00 | 22 | 34.00 | Male | 32.00 | 2.00 | Yes | 2.20 | 7.17 | 43.71 | 0.00 | 6.99 | 36.00 | 0.00 | 23 | 56.00 | Female | 51.00 | 5.00 | Yes | 15.00 | 5.23 | 174.34 | 0.00 | 3.84 | 75.10 | 0.00 | 24 | 29.00 | Female | 18.00 | 11.00 | No | 5.30 | 7.40 | 44.02 | 0.26 | 3.57 | 138.34 | 2.84 | 25 | 49.00 | Female | 36.00 | 13.00 | No | 2.20 | 10.01 | 181.70 | 8.59 | 3.05 | 146.74 | 2.13 | 26 | 33.00 | Female | 16.00 | 17.00 | No | 2.20 | 7.69 | 43.27 | 8.57 | 3.84 | 27.89 | 4.96 | 27 | 61.00 | Female | 58.00 | 3.00 | No | 3.80 | 10.80 | 180.79 | 3.19 | 6.98 | 127.30 | 0.00 | 28 | 47.00 | Female | 36.00 | 11.00 | No | 3.10 | 7.66 | 75.68 | 0.00 | 2.98 | 91.50 | 0.00 | 29 | 23.00 | Male | 19.00 | 4.00 | No | 4.10 | 7.41 | 139.88 | 2.00 | 2.67 | 87.40 | 0.00 | 30 | 54.00 | Female | 32.00 | 22.00 | No | 3.90 | 6.90 | 48.74 | 0.00 | 2.12 | 142.20 | 4.14 | 31 | 49.00 | Female | 36.00 | 13.00 | No | 4.20 | 7.40 | 36.18 | 0.00 | 3.23 | 113.40 | 2.30 | 32 | 31.00 | Female | 18.00 | 13.00 | No | 2.20 | 9.10 | 41.60 | 0.28 | 7.10 | 26.10 | 1.80 |
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