Research Article
Long-Lasting Production of New T and B Cells and T-Cell Repertoire Diversity in Patients with Primary Immunodeficiency Who Had Undergone Stem Cell Transplantation: A Single-Centre Experience
Table 4
Multivariable logistic models investigating factors affecting the probability of having an unrestricted repertoire in HSCT patients.
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OR: odds ratio; SE: standard error. Two models were fitted; reported here are only the significant factors and interactions; predictions of model 2 are depicted in Supplementary Figure 4. GvHD: graft-versus-host disease. TRECs: T-cell receptor excision circles. aTime expressed in months since transplantation; the interaction represents the effect of GvHD on the slope of the regression line (see Supplementary Figure 4); bthis quadratic interaction represents the effect of GvHD on the rate of change of the slope, that is, the curvature of the regression line; c,dthese interactions represent the change of the effect of GvHD on the slope due to the presence or absence of ablative conditioning. |