Association of TNF-α with Impaired Migration Capacity of Mesenchymal Stem Cells in Patients with Systemic Lupus Erythematosus

Table 1

Main clinical characteristics of SLE patients.

Patient number/age/sex	Disease duration, months	SLEDAI score	Clinical manifestations	Treatments before BM puncture
1/24/F	1	13	Febrile, cytopenia, hypohemoglobinemia, thrombocytopenia, nephritis, hypocomplementemia, ANA positive, anti-SM positive, anti-RNP positive	Pred 20 mg/day, HCQ 200 mg/day
2/45/F	216	12	Febrile, nephritis, alopecia, cutaneous vasculitis, cytopenia, hypocomplementemia hypohemoglobinemia, ANA positive, anti-dsDNA positive	Pred 10 mg/day, HCQ 400 mg/day, MMF 1.0 gm/day, CYC 0.4 gm/mo
3/56/F	120	10	Arthralgia, cutaneous vasculitis, nephritis, serositis, interstitial pneumonia, cytopenia, ANA positive	Pred 20 mg/day, HCQ 400 mg/day
4/37F	120	15	Arthralgia, cutaneous vasculitis, febrile, nephritis, cytopenia, hypocomplementemia, interstitial pneumonia, lymphadenectasis, ANA positive, anti-dsDNA positive, anti-RNP positive	Pred 30 mg/day, MMF 0.5 gm/day, CYC 0.4 gm/mo
5/16/F	8	10	Cutaneous vasculitis, arthralgia, febrile, nephritis, cytopenia, hypohemoglobinemia, ANA positive, anti-dsDNA positive, anti-SM positive, anti-RNP positive	Pred 20 mg/day, HCQ 400 mg/day
6/22/F	40	9	Nephritis, cytopenia, thrombocytopenia, serositis, ANA positive, anti-dsDNA positive	Pred 15 mg/day, CYC 0.8 gm/mo, HCQ 400 mg/day

ANA: anti-nuclear antibody, anti-dsDNA: anti-double strand DNA antibody, anti-RNP: anti-ribonuclear protein antibody, anti-SM: anti-Smith antibody, Pred: prednisone, CYC: cyclophosphamide, HCQ: hydroxychloroquine, MMF: mycophenolate mofetil; SLEDAI: SLE disease activity index; BM: bone marrow.