Association of TNF-α with Impaired Migration Capacity of Mesenchymal Stem Cells in Patients with Systemic Lupus Erythematosus

Figure 1

Migration capacity was significantly decreased in BMSCs from SLE patients. (a) The scratches healed faster in BMSCs from healthy controls than that from SLE patients 12 hours after the scratch experiments. The length of average healed gaps was illustrated by the black line. (b) The migration rate of BMSCs from SLE patients was remarkably reduced compared with that of healthy controls by transwell migration assay. Migrated BMSCs stained in Giemsa solution (marked by black arrows in the figure) were quantified by image pro-plus 6.0 software to obtain the migration rate per morphologic field randomly selected. , .

(a)

(b)