Activation of Dendritic Cells by the Novel Toll-Like Receptor 3 Agonist RGC100

Table 1

Comparison of the physicochemical and functional properties of RGC100 and poly(I:C).

	Length	Molecular weight	Chemical structure	Biostability^a	Agonist of
RGC100	100 bp	64.6 KDa	dsRNA	7 days	TLR3
Poly(I:C)	~1500–8000 bp	~1020–5440 KDa	dsRNA ± ssRNA	<5 minutes	TLR3, RLRs^b

 ^aBiostability measured as resistance to serum nuclease; ^bRLR: RIG-I-like receptors.