Clinical Study
DNA Methyltransferase 3B Gene Promoter and Interleukin-1 Receptor Antagonist Polymorphisms in Childhood Immune Thrombocytopenia
Table 2
Distribution of rs2424913 DNMT3B allele and genotype frequencies in children with ITP and controls.
| | ITP children (%) | Controls (%) | OR | 95% CI | P value |
| Genotype frequency | | | | | 0.07 | C/C | 12 (37.5) | 37 (57.8) | | | | C/T | 16 (50) | 25 (39) | 0.5 | 0.2–1.25 | 0.17 | T/T | 4 (12.5) | 2 (3.2) | 0.16 | 0.03–1.0 | 0.053 | Allelic frequency | | | | | 0.03* | Allele C | 40 (62.5) | 99 (77.34) | | | | Allele T | 24 (37.5) | 29 (22.66) | 2 | 1.06–3.94 | |
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