Ectopic Fat Deposition on Insulin Sensitivity: Correlation of Hepatocellular Lipid Content and M Value
Table 3
Body fat composition, HCL, and skeletal muscle fat content.
NGT
IGT
T2DM
P value
BFR (%)
25.22 ± 6.19
31.42 ± 6.47†
30.63 ± 9.54†
0.010
FM index
6.45 ± 2.14
8.24 ± 2.29†
8.28 ± 3.15†
0.022
LM index
18.77 ± 2.15
17.75 ± 2.20
18.11 ± 1.50
0.253
HCL (%)
7.39 ± 3.71
12.27 ± 7.73†
17.37 ± 5.60†‡
0.000
IMCL (sol)
7.88 (6.10–10.12)
8.25 (7.04–10.35)
10.70 (9.10–12.25)
0.208
(mmol/kg)
EMCL (sol)
17.54 (12.32–25.47)
18.62 (10.99–27.41)
22.84 (14.64–44.05)
0.754
(mmol/kg)
IMCL (ta)
1.74 (1.19–2.55)
2.52 (1.57–3.78)
5.20 (2.89–5.28)†
0.025
(mmol/kg)
EMCL (ta)
4.91 (2.56–9.59)
7.82 (3.93–11.01)
5.46 (2.85–9.48)
0.360
(mmol/kg)
Data are presented as the mean ± SD or median (25th–75th). †NGT versus IGT and T2DM , ‡IGT versus T2DM . BFR: body fat ratio, FM index: fat mass index, and LM index: lean mass index; hepatocellular lipid content (HCL), intramyocellular lipid (IMCL), and extramyocellular lipid (EMCL) of tibialis anterior (ta) and soleus muscle (sol).