Research Article

Angioblast Derived from ES Cells Construct Blood Vessels and Ameliorate Diabetic Polyneuropathy in Mice

Table 2

Body weight, blood glucose, and HbA1c levels.

 Normal miceDiabetic mice
Before transplantationAfter transplantationBefore transplantationAfter transplantation
SalineES-ABSalineES-AB

HbA1c (%)4.0 ± 0.14.1 ± 0.24.1 ± 0.27.3 ± 1.4**7.7 ± 2.1##7.7 ± 2.5##
Blood glucose (mmol/L)9.1 ± 1.69.2 ± 1.69.1 ± 1.623.1 ± 2.8**25.8 ± 8.0##24.2 ± 9.0##
Body weight (g)30.6 ± 2.731.3 ± 3.031.9 ± 3.726.1 ± 3.1**25.3 ± 3.2##27.6 ± 1.6##

Results are means ± SD. ES-AB: mice transplanted angioblast-like cells induced from embryonic stem cell. ** versus pretreatment normal mice. ## versus posttreatment normal mice.