Characterization and Compatibility Studies of Different Rate Retardant Polymer Loaded Microspheres by Solvent Evaporation Technique: In Vitro-In Vivo Study of Vildagliptin as a Model Drug

Figure 4

Release of Vildagliptin from microspheres prepared by emulsion solvent evaporation technique, respectively, where (a) zero order is from VF1 to VF3, (b) first order is from VF4 to VF6, (c) Higuchi model is from VF10 to VF12, and (d) Korsmeyer model is from VF13 to VF5.

(a)

(b)

(c)

(d)