Lipoplatin Formulation Review Article

Table 3

Toxicity/statistical differences.

Toxicity grade 1–4	Arm A	Arm B
	n (%)	n (%)	P value*
Anemia	50 (43.9)	62 (54.9)	0.112
Leucopenia (neutropenia)	38 (33.3)	52 (45.2)	0.017
Thrombocytopenia	2 (1.8)	3 (2.6)	1.000^†
Nephrotoxicity (renal)	7 (6.1)	46 (40.0)	<0.001
Neurotoxicity	52 (45.6)	63 (54.8)	0.145
GI toxic nausea/vomiting	37 (32.5)	52 (45.2)	0.042
GI diarrhea	2 (1.8)	3 (2.6)	1.000^†
Asthenia	65 (57.0)	82 (71.3)	0.019
Alopecia	96 (84.2)	87 (75.7)	0.134

GI, gastrointestinal.
*Pearson’s chi-square test.
^†Fisher’s exact test.