Research Article
Optimization of Liposomal Lipid Composition for a New, Reactive Sulfur Donor, and In Vivo Efficacy Studies on Mice to Antagonize Cyanide Intoxication
Table 6
Therapeutic protection by various CN antidotal combinations. Control: KCN LD50 = 7.8 (4.6–13.1) mg/kg.
| | Exp no. | KCN dose (mg/kg) | Treatment | Survival (%) |
| | 1 | 15 | (SL-DTO-TS-Rh) | 6/6 (100%) | | 2 | 15 | (SL-DTO-TS) + SN | 6/6 (100%) | | 3 | 15 | (SL-DTO-TS-Rh) + SN | 6/6 (100%) | | 4 | 20 | (SL-DTO-TS) + SN | 4/6 (67%) | | 5 | 20 | (SL-DTO-TS-Rh) | 6/6 (100%) | | 6 | 20 | (SL-DTO-TS) | 3/6 (50%) | | 7 | 20 | (SL-DTO-TS-Rh) + SN | 6/6 (100%) |
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