High-Resolution Imaging of Dendrimers Used in Drug Delivery via Scanning Probe Microscopy
Figure 1
AFM characterization of paclitaxel- (PTX-) loaded HS-PEG5k-CA8 micelles and unloaded HS-PEG5k-CA8 micelle on gold substrate in aqueous solution. The first column is AFM topography (a), phase image (b) and corresponding cursors of PTX-loaded micelle. AFM topography (c), phase image (d), and corresponding cursors of unloaded micelle are shown in second column. In cursor profiles, areas indicated with red, blue, and grey are relative to PTX-loaded micelle, unloaded micelle and AD SAM, respectively. Height, short axis, and long axis of PTX-loaded micelle extracted from cursors profiles 1, 2, and 3. Height, short axis, and long axis of unloaded micelle extracted from cursors profiles 4, 5, and 6.
