Hypolipidemic Effect of Chloroform Extract of Lagenaria siceraria: Potential Inhibitory Activity of Phytochemicals Targeting the HMG-CoA Reductase Revealed by Molecular Docking and Simulation Studies

Table 2

The binding free energies of the complexes calculated by implying the MM/PBSA module.

Energy components (kcal/mol)	Stigmastan-3-ol	Atorvastatin
	−41.35 ± 0.14	−43.62 ± 0.15
	−3.47 ± 0.08	−4.51 ± 0.09
	−30.28 ± 0.15	−27.69 ± 0.12
	44.31 ± 0.06	48.77 ± 0.09
	21.24 ± 0.08	19.45 ± 0.10
	−44.82 ± 0.17	−43.57 ± 0.16
	45.28 ± 0.09	44.67 ± 0.10
	−9.09 ± 0.15	−6.50 ± 0.17