Neuroprotective Activity of Water Soluble Extract from Chorispora bungeana against Focal Cerebral Ischemic/Reperfusion Injury in Mice

Table 2

Effect of Chorispora bungeana water extract on 8-OHdG expression and cell apoptosis in mice subjected to cerebral ischemia/reperfusion.

Group	Dose (g/kg)	8-OHdG positive cells	TUNEL positive cells
Model	/	20.88±3.31	21.63±4.21
Sham	/	2.13±1.25^∗∗	2.25±1.04^∗∗
Chorispora bungeana	5	16.25±2.60^∗∗	17.13±3.40^∗
Chorispora bungeana	2.5	17.13±3.17^∗	18.25±3.99
Chorispora bungeana	1.25	19.88±3.83	19.50±4.41
Edaravone	0.003	15.38±3.42^∗∗	17.25±3.24^∗

Data were expressed as mean ± S.M.E. Differences were considered significant at 𝑃<0.05. ^∗𝑃<0.05 versus model group. ^∗∗𝑃<0.01 versus model group.