Review Article
Relationships between Global DNA Methylation in Circulating White Blood Cells and Breast Cancer Risk Factors
Table 1
Summary of number of reports by risk factor and global methylation measure.
| Factors | Total # of reports | LINE-1 | Alu | 5-mdC |
| Demographic Factors | | | | | Age | 31 | 21 | 6 | 4 | Sex | 22 | 17 | 4 | 1 | Race/ethnicity | 6 | 5 | 0 | 1 | Education | 7 | 6 | 0 | 1 | Lifestyle factors | | | | | Physical activity | 5 | 5 | 0 | 0 | Alcohol | 17 | 13 | 3 | 1 | Smoking | 22 | 16 | 4 | 2 | Dietary factors | | | | | BMI | 17 | 13 | 3 | 1 | Vegetables | 11 | 11 | 0 | 0 | Fruit | 6 | 6 | 0 | 0 | Folate | 13 | 12 | 0 | 1 | Reproductive factors | | | | | Menopause status | 2 | 1 | 0 | 1 | Fetal birthweight | 1 | 1 | 0 | 0 | Family history of breast cancer | 6 | 4 | 1 | 1 | Age at menarche | 1 | 0 | 0 | 1 | Age at first birth | 1 | 0 | 0 | 1 | Parity | 1 | 0 | 0 | 1 | Hormones | 4 | 3 | 0 | 1 |
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