Research Article

Potassium Current Is Not Affected by Long-Term Exposure to Ghrelin or GHRP-6 in Somatotropes GC Cells

Figure 10

Activation curve of the sustained component of the voltage-dependent K+ current in the cellular line of rat GC somatotropes. (a) Adjustments to the normalized conductance of the GC cells under control conditions, treated with ghrelin 10 nM and GHRP-6 100 nM for 96 h. The data were obtained from the current-voltage curves in Figure 4, the continuous lines representing the adjustment of data with a Boltzmann-type function. (b) Maximum conductance value for each of the experimental conditions. (c) and (d): values of the Boltzmann-type adjustment parameters for each of the experimental conditions, midpoint and slope factor ( ), respectively.
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(a)
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(b)
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(c)
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(d)