Research Article

Immunoreactivity of Pluripotent Markers SSEA-5 and L1CAM in Human Tumors, Teratomas, and Induced Pluripotent Stem Cells

Figure 3

SSEA-5, L1CAM, and ALDH1A1 immunoreactivity in iPS-induced teratoma. (a) Paraffin sections of iPS-induced teratomas were obtained from Stem Cell Technologies and immunostained for both SSEA-5 (red) and L1CAM (green). The same microscopic field is shown. Note that there are some areas of colocalization for SSEA-5 and L1CAM and areas of only L1CAM immunoreactivity. Scale bar = 15 microns. (b) Colocalization of SSEA-5 with the stem cell marker ALDH1A1 is shown in iPS-induced teratoma.
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