Research Article

Consumption of Nuts at Midlife and Healthy Aging in Women

Table 3

Odds of healthy aging, according to frequencies of consumption of specific types of nuts at midlife in the Nurses’ Health Study.

Servings (28 grams for nuts)
<1 per month1–<4 per month1–<2 per week≥2 per week trend

Peanuts
 Healthy agers (n = 5,538), %39.245.67.47.9
 Age-adjusted OR (95% CIs) of healthy vs usual aging1.0 (Ref.)1.01 (0.94, 1.07)1.05 (0.93, 1.18)1.20 (1.06, 1.35)0.011
 Multivariable-adjusteda OR (95% CIs) of healthy vs usual aging1.0 (Ref.)1.00 (0.93, 1.07)0.96 (0.85, 1.10)1.08 (0.95, 1.22)0.524
 Multivariable-adjustedb OR (95% CIs) of healthy vs usual aging1.0 (Ref.)0.99 (0.92, 1.06)0.94 (0.83, 1.07)1.04 (0.92, 1.19)0.960

Peanut butter
 Healthy agers (n = 5,538), %21.538.814.625.2
 Age-adjusted OR (95% CIs) of healthy vs usual aging1.0 (Ref.)0.95 (0.88, 1.03)0.94 (0.85, 1.04)0.94 (0.86, 1.03)0.220
 Multivariable-adjusted2 OR (95% CIs) of healthy vs usual aging1.0 (Ref.)1.00 (0.92, 1.09)1.01 (0.90, 1.12)1.00 (0.91, 1.10)0.946
 Multivariable-adjusted3 OR (95% CIs) of healthy vs usual aging1.0 (Ref.)1.00 (0.92, 1.09)1.00 (0.90, 1.12)0.99 (0.90, 1.09)0.839

Walnuts
 Healthy agers (n = 5,538), %51.840.14.63.5
 Age-adjusted OR (95% CIs) of healthy vs usual aging1.0 (Ref.)1.25 (1.17, 1.33)1.49 (1.29, 1.73)1.63 (1.38, 1.93)<0.0001
 Multivariable-adjusteda OR (95% CIs) of healthy vs usual aging1.0 (Ref.)1.17 (1.10, 1.26)1.25 (1.07, 1.47)1.28 (1.07, 1.53)<0.0001
 Multivariable-adjustedb OR (95% CIs) of healthy vs usual aging1.0 (Ref.)1.14 (1.07, 1.22)1.19 (1.01, 1.39)1.20 (1.00, 1.44)0.0001

Other nuts
 Healthy agers (n = 5,538), %47.039.17.36.6
 Age-adjusted OR (95% CIs) of healthy vs usual aging1.0 (Ref.)1.11 (1.04, 1.19)1.37 (1.22, 1.55)1.35 (1.19, 1.53)<0.0001
 Multivariable-adjusteda OR (95% CIs) of healthy vs usual aging1.0 (Ref.)1.05 (0.98, 1.13)1.19 (1.04, 1.36)1.09 (0.95, 1.25)0.018
 Multivariable-adjustedb OR (95% CIs) of healthy vs usual aging1.0 (Ref.)1.03 (0.96, 1.10)1.14 (1.00, 1.30)1.03 (0.90, 1.18)0.205

aLogistic regression model adjusted for age (years), education in 1992 (registered nurse, bachelor’s degree, master, or doctorate), marital status in 1996 (widowed, married, and single/separated/divorced), census tract median income tract (quintiles), BMI (kg/m2; <22, 22–24.9, 25–29.9, and ≥30), energy intake (quintiles), multivitamin use (yes/no), aspirin use (<1, 1–2, or >2 tablets/week), pack-years of smoking (quintiles), physical activity (quintiles of METs-h/week), and physical function impairment in 2000 (yes/no). All covariates were collected in 1998 unless stated otherwise. bLogistic regression model further adjusted for Alternative Healthy Eating Index-2010 score (quintiles) excluding the component of nuts.