Proteomic Profiling of Mitochondrial Enzymes during Skeletal Muscle Aging

Table 1

List of major profiling studies of the mitochondrial proteome.

Proteomic studies	Mitochondrial protein identification	Reference
Proteomic analysis of human placenta	First comprehensive cataloguing of the mitochondrial proteome, which resulted in the identification of 46 distinct proteins	Rabilloud et al. [70]
Analysis of human and mouse heart	Identification of 680 human mitochondrial proteins and 940 mouse mitochondrial proteins in heart muscle	Taylor et al. [71], Gaucher et al. [72], Zhang et al. [73]
Proteomic profiling of mouse and rat liver	Identification of 182 mouse proteins and 192 rat proteins that are associated with liver mitochondria	da Cruz et al. [74], Fountoulakis et al. [75]
Proteomic profiling of human skeletal muscle	Identification of 823 mitochondrial proteins in human vastus lateralis muscle	Lefort et al. [76]
Proteomic profiling of brown and white adipose cell lines	Identification of 723 mitochondrial proteins in brown adipose cell line and 1,198 mitochondrial proteins in white adipose cell line	Forner et al. [77]
Comparative studies for the establishment of the mammalian mitochondrial proteome from various tissues	Identification of tissue-specific expression patterns of mouse and rat mitochondrial proteins from liver, skeletal muscle, kidney, brain, heart, and various other organs. The most comprehensive comparative study established the mitochondrial protein complement in 14 different tissues	Mootha et al. [67], Forner et al. [68], Reifschneider et al. [69], Pagliarini et al. [78]