Review Article

Mitochondria and PGC-1α in Aging and Age-Associated Diseases

Figure 1

Modulation of PGC-1α and its targets. Regulation of PGC-1α activity on transcriptional and posttranscriptional levels as well as by interaction with inhibitory factors is summarized. The diagram shows the PGC-1α targets that are involved in metabolic regulation of mitochondria. The details are discussed in the text.
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