Research Article

Chemometric Methods for Simultaneous Determination of Candesartan Cilexetil and Hydrochlorothiazide in Binary Combinations

Table 5

Limit of detection (LOD) and limit of quantification (LOQ) of CAN by correction absorbance.

λAdded (µg/mL)Found (µg/mL)
HCTCANHCTCAN

34015014.610.54
250

34015014820.45
250

34015014.960.036
250

34015014.880.51
250

34015014.930.39
250

Mean0.39
SD0.2035
LOD0.94
LOQ2.4

1 calculated using the regression equation of Y = 0.0236x + 0.0311, and the HCT calibration curve at 283 nm.