Chemometric Methods for Simultaneous Determination of Candesartan Cilexetil and Hydrochlorothiazide in Binary Combinations

Table 4

Limit of detection (LOD) and limit of quantification (LOQ) of HCT by correction absorbance.

λ	Added (µg/mL)		Found (µg/mL)
	HCT	CAN	HCT	CAN
340	0	15	0.65	14.67
250
340	0	15	0.23	14.8
250
340	0	15	0.56	14.91
250
340	0	15	0.45	14.89
250
340	0	15	0.38	14.8
250
Mean			0.45
SD			0.1623
LOD			0.93
LOQ			2.1

¹ calculated using the regression equation of Y = 0.0236x + 0.0311 and the HCT calibration curve at 283 nm.